2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid - Names and Identifiers
2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid - Introduction
2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid is an organic compound with the chemical formula C10H8BrFO4. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-Melting point: About 139-142 degrees Celsius
-Solubility: Soluble in some organic solvents, such as ether and ethanol
Use:
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid is an organic synthesis intermediate, commonly used in the synthesis of other organic compounds.
-It has potential antibacterial and antiviral activity in the field of medicine.
Method:
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid can be synthesized by first synthesizing 2-(4-bromo-3-methoxyphenyl) acetic acid, it is then obtained by a difluorination reaction under the action of a fluorinating agent.
-The synthetic steps can be as follows:
1. 4-bromo-3-methoxybenzyl alcohol is esterified with acetic anhydride to obtain 2-(4-bromo-3-methoxyphenyl) acetic acid.
2. Difluorination of 2-(4-bromo-3-methoxyphenyl) acetic acid in the presence of potassium difluoride gives 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid.
Safety Information:
- 2-(4-bromo-3-methoxyphenyl)-2,2-difluoroacetic acid may produce toxic gases at high temperatures or when exposed to open flames.
-Use appropriate protective equipment, such as gloves and goggles as shown in the chemical label.
-Avoid inhalation, ingestion or contact with skin and eyes during operation.
Last Update：2024-04-09 02:00:51